The Best Antibody Drug Conjugates References. [1] unlike chemotherapy, adcs are intended to target and kill tumor cells while sparing healthy cells. Cancer has become the second greatest global health threat, accounting for approximately 10.0 million.
This approach comprises a mab conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface, reducing systemic exposure and therefore toxicity. 2, adc is composed of antibody, cytotoxic payload and chemical. The “biological missile” for targeted cancer therapy introduction.
